New research reveals that people who stop using new slimming jabs like Wegovy and Mounjaro may regain lost weight at a significantly accelerated pace than those who end traditional lifestyle programs.
Published data in a major health publication shows that while obese people often shed a large proportion of their body weight while undergoing treatment, the weight comes back at an estimated rate of nearly a kilo each month once they quit.
"People buying these drugs must be cognizant of the danger of fast rebound weight gain when the treatment ends," stated expert Dr. Susan Jebb.
Such speed of regain means a reversion to pre-treatment mass within about 18 months.
Analyzing Approaches
The research, which reviewed dozens of studies involving over 9,000 of patients, contrasted the results of the injectable medications with other pills.
Researchers emphasize that people who lose weight through lifestyle changes alone generally see a less rapid creep back—approximately 100 grams monthly—post-intervention.
Understanding the Quick Regain
Doctors suggest the mechanism of the drugs explains the heightened rebound.
GLP-1 drugs copy a body's own chemical called GLP-1, which moderates hunger.
"Sustained high doses of the hormone concentrations far above than the body's typical production may cause the system to generate a reduced amount of its own natural GLP-1, and could lessen responsiveness to its actions," noted Dr. Adam Collins, a dietetics researcher.
"Withdrawal of this hormone supplement leads to hunger is unsuppressed, making overeating a significant risk."
A Chronic Condition?
Health authorities recommend the injections for individuals with weight-linked health risks, accompanied by recommended diet and exercise modifications.
Professionals contend that, considering the likelihood of relapse, the therapy might need to be ongoing.
This opinion is supported by drug manufacturers, who state that the results "emphasize the chronic character of excess weight," comparing it to managing conditions like diabetes.
User Testimonies
Users who have come off the medication describe a sudden return of cravings.
"It felt as if a trigger flipping and you're instantly ravenous," described an individual.
This difficulty is exacerbated if individuals have not adopted lasting lifestyle or habit modifications during treatment.
Significant Interest
Figures suggest that millions of adults in the UK have used weight-loss jabs in the last 12 months, with interest being substantial.
- Adoption is higher among women than men.
- The 40s and 50s demographic shows the greatest level of interest.
- A large proportion obtain the medications through private healthcare rather than the NHS.
In conclusion, experts stress that while the jabs are powerful tools for shedding pounds, they are not a permanent solution and maintained weight loss likely depends on ongoing behavioural support.
